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Posted Job Title
Process Development Associate Scientist
Job Profile Title
Resource Technologist C
Job Description Summary
The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with the great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.
The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania, has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the âœgo-toâ organization for public and private partners, who want to participate in the gene therapy space. Currently, we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.
Continuation of all GTP positions is contingent upon grant funding.
Our Vector Core is a state-of-the-art facility which provides vector-related materials and services in support of basic and translational research worldwide, producing vectors in support of IND-enabling research, conduct GLP assays, oversee CMO's in vector production and is expanding to conduct state-of-the art process development.
Due to significant growth, the Vector Core is looking for a new Process Development Associate Scientist to support downstream purification production of and projects related to clinical AAV vectors.
As a Process Development Associate Scientist, you will be responsible for the production and purification of research grade and GMP-comparable AAV vectors for IND-enabling pharmacology and toxicology studies. You will be documenting your activities on batch records for QA review. You will become a subject matter expert in downstream production and work independently on process development projects. You will work both independently and as part of a team to accomplish project goals within specified timelines. Successful candidates will have a familiarity with upstream and downstream biologics manufacturing, tissue culture, column chromatography and other purification processes.
- BS Degree in Biochemical/Chemical Engineering, Biochemistry, Biology, or related disciplines + 5 to 7 years of relevant experience.
- Must have experience in upstream or downstream biologics manufacturing.
- Must have experience with tissue culture, column chromatography, or TFF.
- Must be an independent thinker, meticulous, detail oriented, and analytical.
- Must be highly motivated, have excellent organizational, communication and interpersonal skills.
- Must be able to work independently and as part of a multi-disciplinary team.
Job Location - City, State
Department / School
Perelman School of Medicine
$50,684.00 - $91,232.00
Affirmative Action Statement Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.
Special Requirements Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
Internal Number: JR00017006
About University of Pennsylvania
Penn has a long and proud tradition of intellectual rigor and pursuit of innovative knowledge, begun by Benjamin Franklin in 1740. That tradition lives today through the creativity, entrepreneurship, and engagement of our faculty, students, and staff. Academic life at Penn is unparalleled, with an undergraduate student body of 10,000 from every U.S. state and around the world. The entering class of 2015 is the most talented and diverse in Penn's history. Consistently ranked among the top 10 universities in the country, Penn welcomes an additional 10,000 students to our top-ranked graduate and professional schools.